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L'essentiel de la littérature réçente en Pneumologie

Dans cette rubrique on vous propose une revue de la littérature à travers une sélection d'abstracts d'articles originaux.
On essaiera de vous tenir informé des dernières nouveautés de recherche en matière de Pneumologie. On ne vous fournit que le résumé de l'article et le lien correspondant, pour accéder à l'article en full text vous devez être inscrits à la revue correspondante.
Cliquez ici pour consulter la liste des revues de Pneumologie disponibles en libre accès.



External exposome and allergic respiratory and skin diseases Imprimer Envoyer
Samedi, 17 Mars 2018 06:54
Allergies are complex diseases that result from interactions between multiple genetic and environmental factors. However, the increase in allergies observed in the past decades is explained exclusively by environmental changes occurring in the same period. Presently, the exposome, the totality of specific and nonspecific external environmental exposures (external exposome) to which a subject is exposed from preconception onward and their consequences at the organ and cell levels (internal exposome), is being considered to explain the inception, development, and exacerbations of allergic diseases.
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Biodiversity: The new kid on the block? Imprimer Envoyer
Samedi, 17 Mars 2018 06:54
Children living in inner cities in the United States are at particularly high risk of recurrent wheeze and asthma.1 Not all wheezers in the preschool years progress to chronic asthma, but a majority lose their symptoms around age 3 to 4 years, a phenotype that has been termed transient wheeze.2 However, no valid biomarker distinguishing transient wheeze from asthma exists. Only the developmental trajectory until age 4 to 7 years allows a correct a posteriori categorization.
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Mechanism for Initiation of Food Allergy: Dependence on skin barrier mutations and environmental allergen co-stimulation Imprimer Envoyer
Samedi, 17 Mars 2018 06:54
Mechanisms for the development of food allergy in neonates are unknown but are clearly linked in patient populations to a genetic predisposition towards skin barrier defects. Whether skin barrier defects functionally contribute to development of food allergy is unknown.
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