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L'essentiel de la littérature réçente en Pneumologie

Dans cette rubrique on vous propose une revue de la littérature à travers une sélection d'abstracts d'articles originaux.
On essaiera de vous tenir informé des dernières nouveautés de recherche en matière de Pneumologie. On ne vous fournit que le résumé de l'article et le lien correspondant, pour accéder à l'article en full text vous devez être inscrits à la revue correspondante.
Cliquez ici pour consulter la liste des revues de Pneumologie disponibles en libre accès.



Optimizing the utility of high-resolution computed tomography in diagnosing cryptogenic organizing pneumonia Imprimer Envoyer
Mercredi, 01 Décembre 2010 00:00
Publication year: 2010
Source: Respiratory Medicine, In Press, Corrected Proof, Available online 18 November 2010
Edson, Marchiori , Gustavo, de Souza Porta Meirelles , Gláucia, Zanetti , Bruno, Hochhegger
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The lung permeability index: A feasible measurement of pulmonary capillary permeability Imprimer Envoyer
Mercredi, 01 Décembre 2010 00:00

We performed this study to determine the pulmonary capillary permeability (PCP) measuring radiolabeled human serum albumin leakage into the lung. The objective was to use PCP to differentiate between cardiogenic and non-cardiogenic pulmonary edema etiologies.

Methods: We conducted this study in 10 patients admitted to the intensive care unit who had recently developed bilateral pulmonary infiltrates and required hemodynamic monitoring. In these patients we determined the association among the lung permeability index, cardiac output, pulmonary capillary wedge pressure, myocardial performance index, and the protein content of the bronchoalveolar lavage as expressed by bronchoalveolar lavage (BAL) total protein and BAL-to-serum protein ratio. Twenty...

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Long-term non-invasive ventilation in COPD after acute-on-chronic respiratory failure☆ Imprimer Envoyer
Mercredi, 01 Décembre 2010 00:00

COPD patients who remain hypercapnic after acute respiratory failure requiring mechanical ventilation have a poor prognosis. Long-term nocturnal non-invasive ventilation (NIV) may be beneficial for these patients. We hypothesized that stable patients on long-term NIV would experience clinical worsening after withdrawal of NIV.

Methods: We included 26 consecutive COPD patients (63 ± 6 years, 58% male, FEV1 31 ± 14% predicted) who remained hypercapnic after acute respiratory failure requiring mechanical ventilation. After a six month run-in period, during which all patients received NIV, they were randomised to either continue (ventilation group, n = 13) or to stop NIV (withdrawal group, n = 13). The primary endpoint was time to clinical...

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